One of our members seems to be having a problem with Cura so I thought I'd do a little walk around. When you've been using a piece of software for a very long time, and through various iterations, things that seem obvious aren't to a newcomer.
After loading Cura choose your machine
Once you have a machine that even roughly resembles yours, choose a basic profile
here and then I find a good all round is Draft 0.2mm
from there you should choose to see all settings
Lastly you can save and load from Manage Profiles